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Exploratory Immunologic Differences in Cord Blood from Infants Born into Farming Environments Compared to Nonfarming Environments in MESA

Cross-sectional studies on cord blood of term newborns found both pre- and post-natal environmental exposures are significantly associated with unique patterns of immunologic responses. Specifically, the immune response of infants born into farming environments is associated with increased production of proinflammatory cytokines determined from in vitro culture supernatants after culture with TLR agonists. …